MOBILISE-D (820820)

  https://cordis.europa.eu/project/id/820820

  Horizon 2020 (2014-2020)

  Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement

  Linking digital assessment of mobility to clinical endpoints to support regulatory acceptance and clinical practice (IMI2-2017-13-07)

  drug discovery  ·  multiple sclerosis  ·  sensors  ·  health care services  ·  cardiology

  2019-04-01 Start Date (YY-MM-DD)

  2024-03-31 End Date (YY-MM-DD)

  € 49,911,564 Total Cost


  Description

Optimal treatment of the impaired mobility resulting from ageing and chronic disease is one of the 21st century's greatest challenges facing patients, society, governments, healthcare services, and science. New interventions are a key focus. However, to accelerate their development, we need better ways to detect and measure mobility loss. Digital technology, including body worn sensors, has the potential to revolutionise mobility assessment. The overarching objectives of MOBILISE-D are threefold: to deliver a valid solution (consisting of sensor, algorithms, data analytics, outcomes) for real-world digital mobility assessment; to validate digital outcomes in predicting clinical outcome in chronic obstructive pulmonary disease, Parkinson’s disease, multiple sclerosis, proximal femoral fracture recovery and congestive heart failure; and, to obtain key regulatory and health stakeholder approval for digital mobility assessment. The objectives address the call directly by linking digital assessment of mobility to clinical endpoints to support regulatory acceptance and clinical practice. MOBILISE-D consists of 35 partners from 13 countries with long, successful collaboration, combining the requisite expertise to address the technical and clinical challenges. To achieve the objectives, partners will jointly develop and implement a digital mobility assessment solution to demonstrate that real-world digital mobility outcomes can successfully predict relevant clinical outcomes and provide a better, safer and quicker way to arrive at the development of innovative medicines. MOBILISE-D's results will directly facilitate drug development, and establish the roadmap for clinical implementation of new, complementary tools to identify, stratify and monitor disability, so enabling widespread, cost-effective access to optimal clinical mobility management through personalised healthcare.


  Complicit Organisations

2 Israeli organisations participate in MOBILISE-D.

Country Organisation (ID) VAT Number Role Activity Type Total Cost EC Contribution Net EC Contribution
United Kingdom PFIZER LIMITED (998133396) GB201048427 participant PRC € 333,333 € 0 € 0
Germany FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG (999995408) DE132507686 participant HES € 847,863 € 847,863 € 847,863
Ireland UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (999974359) IE6517386K participant HES € 1,484,050 € 1,484,050 € 1,484,050
Switzerland TAKEDA PHARMACEUTICALS INTERNATIONAL AG (950797493) CHE113444401TVA participant PRC € 141,834 € 0 € 0
United Kingdom THE UNIVERSITY OF SHEFFIELD (999976881) GB648238808 participant HES € 2,207,966 € 2,092,966 € 1,333,077
United Kingdom IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE (999993468) GB649926678 participant HES € 390,540 € 390,540 € 390,540
Ireland ICON CLINICAL RESEARCH LIMITED (931760370) IE8201978R participant PRC € 1,000,000 € 0 € 0
Israel TEVA PHARMACEUTICAL INDUSTRIES LIMITED (923869808) IL557410149 participant PRC € 500,000 € 0 € 0
Switzerland NOVARTIS PHARMA AG (999754557) CHE116268023MWST participant PRC € 14,296,667 € 0 € 0
Sweden ASTRAZENECA AB (999941379) SE556011748201 participant PRC € 1,700,000 € 0 € 0
Spain FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA (951414122) ESG65341695 participant REC € 1,595,906 € 1,595,906 € 1,595,906
United Kingdom UNIVERSITY OF NEWCASTLE UPON TYNE (999985417) GB499672470 coordinator HES € 4,114,525 € 3,854,525 € 3,735,585
Belgium AMGEN (997517058) BE0439652401 participant PRC € 980,454 € 0 € 0
Germany CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL (999839529) DE811317279 participant HES € 972,068 € 972,068 € 972,068
Germany PENUMOLOGISCHES FORSCHUNGSINSTITUTAN DER LUNGENCLINIC GROSSHANSDORF GMBH (908208673) DE193602591 participant PRC € 796,412 € 796,412 € 796,412
Switzerland ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (999973971) CHE116075613TVA participant HES € 993,625 € 993,625 € 993,625
United Kingdom TAKEDA DEVELOPMENT CENTRE EUROPE LTD (972222853) GB726561428 participant PRC € 58,165 € 0 € 0
United Kingdom IXSCIENT LIMITED (999689373) GB832399803 participant PRC € 464,000 € 464,000 € 464,000
Germany MERCK KOMMANDITGESELLSCHAFT AUF AKTIEN (999965241) DE811850788 participant PRC € 500,000 € 0 € 0
Israel THE FOUNDATION FOR MEDICAL RESEARCH INFRASTRUCTURAL DEVELOPMENT AND HEALTH SERVICES NEXT TO THE MEDICAL CENTER TEL AVIV (997919705) IL580007102 participant REC € 1,117,625 € 1,117,625 € 1,117,625
United Kingdom UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE (999859705) GB686994842 participant HES € 432,260 € 432,260 € 432,260
France CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER (999609348) FR80263400160 participant REC € 514,685 € 514,685 € 514,685
Italy UNIVERSITA DEGLI STUDI DI SASSARI (999465594) IT00196350904 participant HES € 391,250 € 391,250 € 391,250
Switzerland UNIVERSITAT ZURICH (999976396) CHE115665634MWST participant HES € 532,500 € 532,500 € 532,500
Germany ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH (998562427) DE147799447 participant REC € 2,645,296 € 2,645,296 € 2,645,296
Italy ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA (999993953) IT01131710376 participant HES € 855,665 € 855,665 € 855,665
United Kingdom AMGEN LIMITED (950126835) GB538389011 participant PRC € 20,212 € 0 € 0
Netherlands MCROBERTS BV (968762475) NL008852716B01 participant PRC € 592,187 € 592,187 € 592,187
Germany GRUNENTHAL GMBH (968074454) DE121737755 participant PRC € 85,000 € 0 € 0
Germany BAYER AKTIENGESELLSCHAFT (918419281) DE123659859 participant PRC € 3,050,000 € 0 € 0
France SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT (998198095) FR67713002269 participant PRC € 375,000 € 0 € 0
United States ERESEARCH TECHNOLOGY INC (905175871) nan participant PRC € 1,100,000 € 0 € 0
Germany UNIVERSITATSKLINIKUM ERLANGEN (999866495) DE248558812 participant HES € 1,125,055 € 1,125,055 € 1,125,055
Belgium KATHOLIEKE UNIVERSITEIT LEUVEN (999991334) BE0419052173 participant HES € 831,661 € 831,661 € 831,661
United Kingdom THE NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST (999600521) GB654968777 thirdParty PUB € 118,940 € 0 € 118,940
Norway NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU (999977851) nan participant HES € 2,161,648 € 2,161,648 € 2,161,648
United Kingdom SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST (996615055) GB654400165 thirdParty REC € 759,888 € 0 € 759,888
Italy UNIVERSITA VITA-SALUTE SAN RAFFAELE (999854467) IT13420850151 participant HES € 704,105 € 704,105 € 704,105