MOBILISE-D (820820)
https://cordis.europa.eu/project/id/820820
Horizon 2020 (2014-2020)
Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement
Linking digital assessment of mobility to clinical endpoints to support regulatory acceptance and clinical practice (IMI2-2017-13-07)
drug discovery · multiple sclerosis · sensors · health care services · cardiology
2019-04-01 Start Date (YY-MM-DD)
2024-03-31 End Date (YY-MM-DD)
€ 49,911,564 Total Cost
Description
Optimal treatment of the impaired mobility resulting from ageing and chronic disease is one of the 21st century's greatest challenges facing patients, society, governments, healthcare services, and science. New interventions are a key focus. However, to accelerate their development, we need better ways to detect and measure mobility loss. Digital technology, including body worn sensors, has the potential to revolutionise mobility assessment. The overarching objectives of MOBILISE-D are threefold: to deliver a valid solution (consisting of sensor, algorithms, data analytics, outcomes) for real-world digital mobility assessment; to validate digital outcomes in predicting clinical outcome in chronic obstructive pulmonary disease, Parkinson’s disease, multiple sclerosis, proximal femoral fracture recovery and congestive heart failure; and, to obtain key regulatory and health stakeholder approval for digital mobility assessment. The objectives address the call directly by linking digital assessment of mobility to clinical endpoints to support regulatory acceptance and clinical practice. MOBILISE-D consists of 35 partners from 13 countries with long, successful collaboration, combining the requisite expertise to address the technical and clinical challenges. To achieve the objectives, partners will jointly develop and implement a digital mobility assessment solution to demonstrate that real-world digital mobility outcomes can successfully predict relevant clinical outcomes and provide a better, safer and quicker way to arrive at the development of innovative medicines. MOBILISE-D's results will directly facilitate drug development, and establish the roadmap for clinical implementation of new, complementary tools to identify, stratify and monitor disability, so enabling widespread, cost-effective access to optimal clinical mobility management through personalised healthcare.
Complicit Organisations
2 Israeli organisations participate in MOBILISE-D.Country | Organisation (ID) | VAT Number | Role | Activity Type | Total Cost | EC Contribution | Net EC Contribution |
---|---|---|---|---|---|---|---|
United Kingdom | PFIZER LIMITED (998133396) | GB201048427 | participant | PRC | € 333,333 | € 0 | € 0 |
Germany | FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG (999995408) | DE132507686 | participant | HES | € 847,863 | € 847,863 | € 847,863 |
Ireland | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (999974359) | IE6517386K | participant | HES | € 1,484,050 | € 1,484,050 | € 1,484,050 |
Switzerland | TAKEDA PHARMACEUTICALS INTERNATIONAL AG (950797493) | CHE113444401TVA | participant | PRC | € 141,834 | € 0 | € 0 |
United Kingdom | THE UNIVERSITY OF SHEFFIELD (999976881) | GB648238808 | participant | HES | € 2,207,966 | € 2,092,966 | € 1,333,077 |
United Kingdom | IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE (999993468) | GB649926678 | participant | HES | € 390,540 | € 390,540 | € 390,540 |
Ireland | ICON CLINICAL RESEARCH LIMITED (931760370) | IE8201978R | participant | PRC | € 1,000,000 | € 0 | € 0 |
Israel | TEVA PHARMACEUTICAL INDUSTRIES LIMITED (923869808) | IL557410149 | participant | PRC | € 500,000 | € 0 | € 0 |
Switzerland | NOVARTIS PHARMA AG (999754557) | CHE116268023MWST | participant | PRC | € 14,296,667 | € 0 | € 0 |
Sweden | ASTRAZENECA AB (999941379) | SE556011748201 | participant | PRC | € 1,700,000 | € 0 | € 0 |
Spain | FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA (951414122) | ESG65341695 | participant | REC | € 1,595,906 | € 1,595,906 | € 1,595,906 |
United Kingdom | UNIVERSITY OF NEWCASTLE UPON TYNE (999985417) | GB499672470 | coordinator | HES | € 4,114,525 | € 3,854,525 | € 3,735,585 |
Belgium | AMGEN (997517058) | BE0439652401 | participant | PRC | € 980,454 | € 0 | € 0 |
Germany | CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL (999839529) | DE811317279 | participant | HES | € 972,068 | € 972,068 | € 972,068 |
Germany | PENUMOLOGISCHES FORSCHUNGSINSTITUTAN DER LUNGENCLINIC GROSSHANSDORF GMBH (908208673) | DE193602591 | participant | PRC | € 796,412 | € 796,412 | € 796,412 |
Switzerland | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (999973971) | CHE116075613TVA | participant | HES | € 993,625 | € 993,625 | € 993,625 |
United Kingdom | TAKEDA DEVELOPMENT CENTRE EUROPE LTD (972222853) | GB726561428 | participant | PRC | € 58,165 | € 0 | € 0 |
United Kingdom | IXSCIENT LIMITED (999689373) | GB832399803 | participant | PRC | € 464,000 | € 464,000 | € 464,000 |
Germany | MERCK KOMMANDITGESELLSCHAFT AUF AKTIEN (999965241) | DE811850788 | participant | PRC | € 500,000 | € 0 | € 0 |
Israel | THE FOUNDATION FOR MEDICAL RESEARCH INFRASTRUCTURAL DEVELOPMENT AND HEALTH SERVICES NEXT TO THE MEDICAL CENTER TEL AVIV (997919705) | IL580007102 | participant | REC | € 1,117,625 | € 1,117,625 | € 1,117,625 |
United Kingdom | UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE (999859705) | GB686994842 | participant | HES | € 432,260 | € 432,260 | € 432,260 |
France | CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER (999609348) | FR80263400160 | participant | REC | € 514,685 | € 514,685 | € 514,685 |
Italy | UNIVERSITA DEGLI STUDI DI SASSARI (999465594) | IT00196350904 | participant | HES | € 391,250 | € 391,250 | € 391,250 |
Switzerland | UNIVERSITAT ZURICH (999976396) | CHE115665634MWST | participant | HES | € 532,500 | € 532,500 | € 532,500 |
Germany | ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH (998562427) | DE147799447 | participant | REC | € 2,645,296 | € 2,645,296 | € 2,645,296 |
Italy | ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA (999993953) | IT01131710376 | participant | HES | € 855,665 | € 855,665 | € 855,665 |
United Kingdom | AMGEN LIMITED (950126835) | GB538389011 | participant | PRC | € 20,212 | € 0 | € 0 |
Netherlands | MCROBERTS BV (968762475) | NL008852716B01 | participant | PRC | € 592,187 | € 592,187 | € 592,187 |
Germany | GRUNENTHAL GMBH (968074454) | DE121737755 | participant | PRC | € 85,000 | € 0 | € 0 |
Germany | BAYER AKTIENGESELLSCHAFT (918419281) | DE123659859 | participant | PRC | € 3,050,000 | € 0 | € 0 |
France | SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT (998198095) | FR67713002269 | participant | PRC | € 375,000 | € 0 | € 0 |
United States | ERESEARCH TECHNOLOGY INC (905175871) | nan | participant | PRC | € 1,100,000 | € 0 | € 0 |
Germany | UNIVERSITATSKLINIKUM ERLANGEN (999866495) | DE248558812 | participant | HES | € 1,125,055 | € 1,125,055 | € 1,125,055 |
Belgium | KATHOLIEKE UNIVERSITEIT LEUVEN (999991334) | BE0419052173 | participant | HES | € 831,661 | € 831,661 | € 831,661 |
United Kingdom | THE NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST (999600521) | GB654968777 | thirdParty | PUB | € 118,940 | € 0 | € 118,940 |
Norway | NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU (999977851) | nan | participant | HES | € 2,161,648 | € 2,161,648 | € 2,161,648 |
United Kingdom | SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST (996615055) | GB654400165 | thirdParty | REC | € 759,888 | € 0 | € 759,888 |
Italy | UNIVERSITA VITA-SALUTE SAN RAFFAELE (999854467) | IT13420850151 | participant | HES | € 704,105 | € 704,105 | € 704,105 |