IMPACT (101188848)

  https://cordis.europa.eu/project/id/101188848

  Horizon Europe (2021-2027)

  Immune Photo-Activated Cancer Therapy for the Treatment of Upper Tract Urothelial Cancer (UTUC) and other solid tumours

  EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOROPEN-01)

  surgery  ·  oncology  ·  laser physics

  2024-12-01 Start Date (YY-MM-DD)

  2026-11-30 End Date (YY-MM-DD)

  € 0 Total Cost

  Description

UTUC is a non-systemically treatable cancer that forms in the renal pelvis or ureter, frequently recurring due to ineffective systemic chemotherapy. With 5-10% of urothelial cancers being UTUC, current surgical treatment solutions pose significant hardships on patients and decrease their quality of life. Our proprietary solution, Padeliporfin-VTP therapy, offers a minimally invasive and effective alternative to surgery. This therapy delivers an inactive photosensitizer drug that is precisely activated in the tumour micro-environment by non-thermal laser light, immediately impeding the tumour's blood supply, leading to cell death with minimal effect on healthy tissues. This treatment not only effectively eliminates tumours, but also preserves organ functionality for potential future treatments. This project is led by a team of accomplished professionals in the pharmaceutical and biopharma industry, which solidifies our capability in innovating best-in-class therapeutic solutions. Utilising this funding, we aim to achieve regulatory approval (TRL9), scale production, and achieve market penetration in a market projected to reach €4.39B by 2032.

  Complicit Organisations

1 Israeli organisation participates in IMPACT.